Cbl-b deficiency increases macrophage recruitment in vivo. (A) The numbers of macrophages in WT (□) or Cbl-b^−/− (■) mice are shown at 0 hours and 72 hours after intraperitoneal injection of thioglycollate solution. (B) Thioglycollate-induced peritonitis in WT mice sublethally irradiated and reconstituted with bone marrow cells from WT mice (WT → WT), or with bone marrow cells from Cbl-b^−/− mice (Cbl-b^−/− → WT). Data are expressed as absolute numbers of emigrated macrophages into the peritoneum. Data are means plus or minus SD (n = 3-9 mice/group). ^#P < .01; *P < .05; ns, nonsignificant.