Effect of D609 on gp120-mediated secretion of CCL3 and CCL4 in MDMs. Monocytes were seeded, cultured, and treated as described in the legend to Figure 1B. After 24 hours of culture, supernatants were harvested and frozen prior to CCL3 (A) and CCL4 (B) determination. Data are the means (± SD) of the results obtained with 3 different donors. *P < .05; **P < .005.