Temporal changes in serum IgM and sCD27 levels in WM patients. Serial (A,B) and correlative (C) changes in serum IgM and sCD27 levels in 31 patients with WM (WM 1-9, stable disease; WM 10-16, progressive disease; and WM 17-31, responders) whose outcomes were determined by consensus panel response criteria.²³  (C) Diagonal line represents line of best fit.