Figure 2
Janus homology domains of the JAK family of kinases. The V617F mutation is within the JH2, or pseudokinase domain, whereas the exon 12 mutations in JAK2 are proximal to the JH2 domain. Illustration by Debra Tyler.
Janus homology domains of the JAK family of kinases. The V617F mutation is within the JH2, or pseudokinase domain, whereas the exon 12 mutations in JAK2 are proximal to the JH2 domain. Illustration by Debra Tyler.
