Phenotypic characterization of viperin−/− mice. (A,B) Representative CD3/CD19 (A) and CD4/CD8 (B) profiles in splenocytes from 6-week-old wild-type and viperin−/− mice. The numbers in quadrants indicate the percentage of each quadrant. (C,D) Surface expression of CD44, CD62L, CD3, IL-4Rα, and common γc was analyzed on the splenic CD4+ T-cell population from viperin−/− mice (solid line) and its wild-type controls (dotted line). Background staining is shown as hatched areas. Data are representative of 3 independent experiments.