Recruitment of primitive myeloid cells to embryonic wound sites in Xenopus laevis. spib (A-C), mpo (XPOX2) (D,E), and scl (G-I) whole mount in situ hybridization in wounded embryos. Three hours is sufficient for the recruitment of myeloid cells expressing spib or mpo to the scrape wound outline (dashed line contour in the inset). scl-expressing cells are not recruited to the wound site, and primitive myeloid cell recruitment occurs before the appearance of a fully functional vascular network.