Figure 3
Increased copies of chromosome 18 in the patient leukemia cells (n = 82, evaluated by 600 000 SNP-chip data) were associated with higher MTXPG accumulation (P = 3.13 × 10−8, ANOVA). Fourteen of the 15 patients with a gain of copy number of chromosome 18 had B-hyperdiploid subtype. Black circles represent B-hyperdiploid; red circles, B-other; light blue circles, T-lineage; dark blue circles, TEL-AML1; green circles, E2A-PBX1.
