In vivo antineoplastic activity of mIFN-α1-LV. Kaplan-Meier survival curves for CRO-AP/3–injected SCID mice treated with mIFN-α1-LV. Data were obtained from 2 separate experiments of 15 animals each (5 mice per group). mIFN-α1-LV–treated mice showed a statistically significant increase in survival time compared to control mice.