MCL cell lines demonstrate a high level of CXCR4 and CXCR5 expression. Overlay histogram plots depict the relative CXCR4 and CXCR5 fluorescence intensity (bold line) of CD19⁺ MCL cells in comparison with isotype control stain (thin line). The MFIRs are displayed next to each histogram. The MCL lines SP-53, MINO, and JeKo-1 demonstrate high levels of CXCR4 and CXCR5 expression, whereas in the EBV⁺ cell line Granta 519 expression of these chemokine receptors is low.