Trafficking of MKO neutrophils is altered in mixed chimeras. Whole bone marrow from wild-type (WT, Ly5.1) and MKO (Ly5.2) mice was mixed in a 1:1 ratio and transplanted into lethally irradiated wild-type (Ly5.1) recipients. After hematopoietic reconstitution (8-10 weeks), the bone marrow and blood were analyzed by flow cytometry. The numbers at the top of the columns indicate the fold increase over the wild-type cells. (A) Mature neutrophils (Gr-1^bright CD115⁻). (B) Neutrophil distribution index. (C) B lymphocytes (B220⁺). The data represent the mean ± SEM of n = 18 recipients from 2 separate transplants. *P < .05 compared with wild-type cells.