Pedigrees of familial TACI deficiency. Pedigrees of 7 families with TACI deficiency are shown. Symbols: circles indicate female; squares, male; black filled symbols, CVID; gray filled symbols, IgG subclass deficiency or dysgammaglobulinemia; hatched symbols, selective IgA deficiency; slash, deceased; and arrow, index patient. Mutations shown in brackets are inferred. §IDs refer to Voerechovsky et al.³³