Platelet accumulation in ruby-eye mice after laser-induced injury of cremaster arterioles. (A) Platelet accumulation was imaged at the indicated time intervals, after injury, in both wild-type (WT) and ruby-eye mice. (B) Median integrated platelet fluorescence intensity was recorded at each second for 180 seconds after laser injury in ruby-eye mice. (C) At 30 seconds, median platelet accumulation in ruby-eye mice was 22% of WT (P = .001). Maximal thrombus size in ruby-eye mice was decreased compared with WT mice (12% of WT; P = .001). By 180 seconds, median platelet accumulation in ruby-eye mice was 31% of WT mice (P = .007).