miR-34a expression in CD19+ B-CLL cells normalized to CD19+ B cells of healthy controls. Significantly lower expression was found in B-CLL patients with (A) p53 deletions or mutations, (B) the SNP309 G/G genotype, and (C) attenuated p53 (p53 del/mut, SNP309 G/G, del 11q). Box length equals interquartile range (**P < .01).