Treatment-free survival of B-CLL patients with or without alterations in the p53 axis. (A) p53 del/mut, (B) p53-attenuated (p53 del/mut, SNP309 G/G, del11q), (C) low or high miR-34a expression, and (D) correlation of miR-34a expression with lymphocyte doubling time. Box length equals interquartile range (**P < .01).