Deficits in ISG induction are not significantly correlated with deficits in IFNα/βR expression. Univariate linear regression analysis was used to assess relationships of ISG gene induction (Figure 4) with IFNα/βR expression. For uninfected subjects, induction of MxA (A) and OAS (B) was not significantly related to monocyte IFNα/βR expression (P = .186 and P = .652, respectively). Similarly, for HIV-1–infected subjects, induction of MxA (C) and OAS (D) was not significantly related to IFNα/βR expression (P = .936 and P = .301, respectively).