Depletion of pFn enhanced thrombus formation in Cre+ TKO mice in a FeCl3-injury mesenteric arteriole thrombosis model. (A) No significant difference was observed in early platelet deposition (shown at 4 minutes), but thrombus growth (shown at 15 minutes) and vessel occlusion (27 minutes) were accelerated. The arrow in the Cre− panel (27 minutes) shows blood flow from right to left in the arteriole. (B) Quantitative analysis of thrombus formation in Cre+ TKO mice () and Cre− control (■) mice. Cre+ TKO mice, n = 9; Cre− control mice, n = 10.