Plasma D-dimer levels are increased in HIV infection and correlate with the proportion of monocytes expressing TF. Plasma was collected from whole-blood samples provided by HIV-infected (n = 38) and -uninfected donors (n = 18), and levels of D-dimers were measured. (A) Levels of D-dimers are higher in plasma samples from HIV-infected patients than in samples from HIV-uninfected controls (P = .032). (B) Plasma levels of D-dimers correlate with the proportion of TF⁺ monocytes in all samples tested (r = 0.37, P = .007).