Analysis of purified fibrinogen. Samples of variant fibrinogen (1 μg) from CTEPH patients (patients nos. 1-5) as well as normal fibrinogen from a representative healthy control (C) were subjected to SDS PAGE (10% reducing gel) followed by staining with colloidal blue. Mobilities of the fibrinogen chains (Aα, Bβ, γ) and molecular mass markers (kilodaltons) are shown.