B-cell chemotaxis does not require talin1. (A) FACS staining for CXCR4 (left) and CXCR5 (right) expression on CD19Tln1^−/− mice (talin null) and WT spleen-derived B cells. (B) The B cells analyzed in panel A were compared for their ability to migrate toward different concentrations of CXCL12 (left) and CXCL13 (right). Results are the mean ± SD of triplicates and are representative of 2 independent experiments.