Lack of phenotypic and functional perturbations in peripheral blood γδ T cells during natural SIVagm infection. (A) Vδ1/Vδ2 ratio from infected (inverted triangles) and uninfected (triangles) AGMs. (B) Percentage of Vδ1 T cells expressing CD28 and CCR5 in infected and uninfected AGMs. (C) Percentage of Vδ2 T cells expressing CD28 and CCR5 in infected and uninfected AGMs. (D) Percentage of Vδ1 and Vδ2 T cells that express Ki67 in infected and uninfected AGMs. (E) IL-17 and IFNγ expression in PMA/ionomycin–stimulated peripheral blood Vδ1 and Vδ2 T cells from infected and uninfected AGMs. (F) Volumetric Vδ1 and Vδ2 T-cell counts in peripheral blood of uninfected and chronically SIV-infected AGMs. P values were calculated using the Mann-Whitney U test.