JAK2^V617F mice exhibit enhanced erythroid and megakaryocyte differentiation. (A) Representative FACS profiles stained with CD71 and Ter119 antibodies are shown; i through v correspond to progressive stages of erythroid differentiation. (B) Histograms show increased terminal erythroid differentiation in JAK2^V617F mice BM at 6 and 26 weeks after pIpC. *P < .05. **P < .01. Data are mean ± SEM. (C) Increased megakaryocyte ploidy in JAK2^V617F mice. FACS profiles for megakaryocytes grown in liquid culture are shown. Histograms represent results from 2 independent experiments. *P < .05. **P < .01. Data are mean ± SEM.