TG parameters in the placebo or 80-μg/kg groups in experiment 2. TG parameters in subjects treated with placebo or 80 μg/kg rFVIIa at (A) lag time, (B) time to maximum concentration, (C) maximum concentration, and (D) endogenous thrombin potential. B0 indicates biopsy 0 (before warfarin treatment); B1, biopsy 1 (after warfarin treatment to achiever INR of 2.5 ± 0.3); B2, biopsy 2 (15 minutes after rFVIIa or placebo treatment). Arrow indicates time of rFVIIa administration.