Survival of mice with abrogated uPA-uPAR interaction. The 1-year survival of a prospective cohort of Plau^+/+ (n = 8), Plau^GFDhu/GFDhu (n = 9), Plaur^−/− (n = 7), and Plau^−/− (n = 7) mice. P < .01, Plau^−/− versus other genotypes, log rank test, 2-tailed.