Loss of uPA-uPAR interaction does not affect leukocyte accumulation in standard models of inflammation. (A and A') Peritoneal neutrophils (CD11b⁻Gr1⁺) at 4 hours and (B) macrophages (CD11b⁺Gr1⁻) at 72 hours after thioglycollate injection of Plau^+/+ (left), Plau^GFDhu/GFDhu (second left), Plaur^−/− (third left), and Plau^−/− (right) mice. Experiments in A and A' were performed on separate days. (C) Lipopolysaccharide-elicited lung neutrophils (CD11b⁻Gr1⁺) at 24 hours in Plau^+/+ (left), Plau^GFDhu/GFDhu (second left), Plaur^−/− (third left), and Plau^−/− (right) mice. Symbols represent individual mice. Horizontal bars show average values. P = N.S., all genotypes versus each other, Mann-Whitney U test, 2-tailed.