Identification of candidate HOXB4 target genes and validation of their expression. (A) Hierarchical cluster diagram and heat map of the 77 candidate probe sets selected from 4 biologically independent experiments using the log₂-ratio of TAM-induced HOXB4-ER^T2 versus TAM-induced GFP expression values observed within each of the 4 experiments. (B) Functional classification of the 77 probe sets using Gene Ontology annotations. Some probe sets were classified into more than 1 category; thus, the sum of all 11 groups is more than 77. (C) Quantitative real-time PCR confirmation of the expression change of the selected 8 candidate target genes from independent experiments with TAM treatment for 6 hours or 12 hours in HOXB4-ER^T2 vector-transduced and GFP control-transduced Lin⁻ BM cells.