Figure 1
Figure 1. miR-155* and miR-155 show the highest induction in human PDCs upon TLR7 stimulation. (A) Taqman Human MicroRNA Arrays analysis of miRNA expression in PDCs after stimulation with R837. Human PDCs were stimulated with 10 μg/mL R837 for 4 hours. RNA was extracted and used for a microarray analysis to determine the expression levels of 657 human miRNAs. Data are presented on a scatter plot showing averaged log2-transformed relative expression (-▵Ct) performed on 2 different PDC preparations of each miRNA for media control (x-axis) and sample stimulated with R837 (y-axis). (B) The RNA used in panel A was analyzed by TaqMan MicroRNA Expression Assay to assay the expression of miR-155* and miR-155. Expression levels were normalized to RNU48.

miR-155* and miR-155 show the highest induction in human PDCs upon TLR7 stimulation. (A) Taqman Human MicroRNA Arrays analysis of miRNA expression in PDCs after stimulation with R837. Human PDCs were stimulated with 10 μg/mL R837 for 4 hours. RNA was extracted and used for a microarray analysis to determine the expression levels of 657 human miRNAs. Data are presented on a scatter plot showing averaged log2-transformed relative expression (-▵Ct) performed on 2 different PDC preparations of each miRNA for media control (x-axis) and sample stimulated with R837 (y-axis). (B) The RNA used in panel A was analyzed by TaqMan MicroRNA Expression Assay to assay the expression of miR-155* and miR-155. Expression levels were normalized to RNU48.

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