Effect of C-terminal FX activation peptide on the half-life of FVIIa. Mean plasma concentration of FVIIa antigen as a function of time after intravenous administration of 1 mg/kg FVIIa and FVIIa_X_HC to mice. Blood was sampled in a sparse schedule as each compound was administered to a total of 6 mice and 3 samples were taken from each animal as described in “Pharmacokinetics.”