Intraluminal crawling of leukocytes in trauma-stimulated cremaster muscle venules. Intraluminal crawling was observed in WT mice (n = 3), LysEGFP mice (n = 6), RAGE^−/− mice (n = 3), Icam1^−/− mice (n = 3), and RAGE^−/−Icam1^−/− mice (n = 3). Intraluminal crawling was quantified as the number of crawling leukocytes to all leukocytes attached (firmly adherent and crawling) to the endothelial wall. Experiments were recorded by time-lapse intravital microscopy at a frame rate of 20 frames/minute over 10 minutes (supplemental Videos 1-3). *Significant differences versus WT mice (P < .05). Data are mean ± SEM.