Differential role of SBSs on IL-5 expression. (A) A schematic of IL-5 promoter constructs with different combinations of SBSs deleted used in the reporter assay. (B) Buffy coat CD4+ T cells were nucleofected with pSUPER-H-2Kk-Scramble2-shRNA construct and WT IL-5 luciferase reporter vector or its SBS deleted version. Data represent mean ± SD of 3 independent experiments.