Frequency (number of cases) of numerical and structural ACAs. (A) Numerical ACAs. Gains are shown on the positive y-axis, and losses are shown on the negative y-axis. Chromosomes are on the x-axis. (B) Structural ACAs The short arms (p) of the chromosomes are shown on the positive y-axis and the long arms (q) on the negative y-axis. Lightest shades are used for losses, medium-shaded colors are used for gains, and the darkest-shaded colors for breakpoints of balanced translocations. Chromosomes are on the x-axis. Balanced 11q23 translocations are not included in the figure.