Pathologic features of the skin biopsy from patient 2. (A) Atypical T lymphocyte infiltration (hematoxylin-eosin stain; original magnification 20×10). (B) Immunohistochemistry stain shows tumor cells expressing CD3 (original magnification 20×10). (C) Immunohistochemistry stain shows tumor cells expressing TIA-1 (original magnification 20×10). (D) In situ hybridization of EBV-RNA.