Structure of LMO2:LDB1-LID and its sequence alignment with LMO1, LMO3, and LMO4. (A) Schematic representation of the topology of the LMO2:LDB1-LID complex. LMO2 is colored in green, and the LID domain of LDB1 in magenta. β-strands are colored in yellow, helices in red, and zinc atoms in gray. (B) Ribbon diagram showing the LMO2:LDB1-LID complex. Close-up of residues interacting with each zinc finger. (C) Residue conservation between human LMO1, LMO2, LMO3, and LMO4. Conserved amino acids drawn in red boxes; similar amino acids in red type. Residues involved in zinc fingers are marked with a gray sphere, the 2 residues located at the hinge region are marked with a blue triangle, and the residues interacting with LDB1 R360 are marked with a red square.