OS according to algorithms obtained by assessments of CD10, BCL6, and MUM1 scoring results. Algorithms were used to define an adjusted GCB/non-GCB index (with the MUM1 cut point defined as 25%) or the LLBC GCB/non-GCB index (with the MUM1 cut point defined as 75%) in the r-CHOP (A and D), c-CHOP (B and E), and e-CHOP (C and E), respectively. Among the 1046 patients scored using the adjusted GCB algorithm and with complete IPI data, 558 were CD10⁺ (GCB), 151 were CD10⁻/BCL6⁺/MUM1⁻ (GCB), 242 were CD10⁻/BCL6⁺/MUM1⁺ (non-GCB), and 95 were CD10⁻/BCL6⁻ (non-GCB). Among the 1046 patients scored using the LLBC GCB algorithm and with complete IPI data, 558 were CD10⁺ (GCB), 270 were CD10⁻/BCL6⁺/MUM1⁻ (GCB), 123 were CD10⁻/BCL6⁺/MUM1⁺ (non-GCB), and 95 were CD10⁻/BCL6⁻ (non-GCB).