Prognostic model using biomarkers and IPI. (A) Hierarchical tree model. Numbers indicate the number of deaths observed at each level in the population at risk. (B) Number of patients, 4-year OS, and HR for the risk of death (without and with imputation for samples with missing scores) in the r-CHOP cohort. (C) OS for r-CHOP patients according to the IPI and the biomarker and IPI model, respectively. Log-rank P values for both models were < .0001.