miRs-126/126* reduced the frequency of erythroid progenitors during EB differentiation. (A) Representative flow cytometric analysis of cell surface markers CD71 and CD235a of day 15 EB cells. Numbers indicate the percentage of cells within each category. (B) miRs-126/126* increased levels of apoptosis of CD71⁺CD235a⁺ cells of day 15 EBs. (C) miRs-126/126* induction suppressed expression of embryonic and fetal globins of day 15 EB cells. Values of fold change in expression are relative to cells without Dox treatment. Data are mean ± SD (n = 3). **P < .01.