Table 2.
Estimated incidence of a first episode of VTE in carriers of various thrombophilic defects (data apply to individuals with at least one symptomatic first-degree relative)
Figures are derived from numerous family studies that are reviewed in detail elsewhere.2
*Based on pooled overall risk of 18 (range, 8-40) and an incidence of 0.1% in noncarriers.
†These risk estimates largely reflect the situation before thrombosis prophylaxis was routine patient care.
‡Data are from family studies, and risk estimates are lower in other settings.
