In vitro cell-viability assays in primary patient samples and cell lines (Reh and RS4:11). Summary graph representing the effect of all agents at 48-hour time point either individually or in combination in Reh cell lines (A), RS4:11 cell lines (B), relapse patient samples (C), and diagnosis patient samples (D) are shown. The x-axis represents the vorinostat and decitabine concentrations at 0, 0.1, 0.5, 1, 2.5, and 5μM and prednisolone at 0, 100, 200, 300, 400, and 500 μg/mL, respectively. The y-axis shows the percent survival.