Figure 2.
Pathways that support platelet activation. A summary of some of the major signaling pathways and events of platelet activation. Further details in the text. PLC, phospholipase C; PKC, protein kinase C; IP3, inositol-1,4,5-trisphosphate; αIIbβ, refers to the platelet integrin that is also known as GP IIb-IIIa in older literature; IP and TP, PGI2 and TxA2 receptors.