Figure 1.
Metabolism of clopidogrel. Schematic representation of the main enzymatic pathways involved in the metabolism of clopidogrel. The role of PON-1 in clopidogrel metabolism is still controversial. CYP indicates cytochrome P450 isoenzyme; PON, paraoxonase; ES, carboxylesterase; BChE, butyrylcholinesterase.