Agents undergoing investigation in CLL
Akt, Ak transforming; bcl, b-cell lymphoma; BH-3, Bcl-2 homology domain 3; Btk, Bruton's tyrosine kinase; CDK, cyclin-dependent kinase; CXCR4, CXC chemokine receptor; HDAC, histone deacetylase; IMID, immunomodulator; JNK, c-Jun N-terminal kinase; MAPK, mitogen-activated protein kinase; mcl, myeloid cell leukemia; PI3K, phosphatidylinositol 3-kinase; PKC, protein kinase C; SMIP, small modular immunopharmaceutical; src, sarcoma; syk, spleen tyrosine kinase; VEGF, vascular endothelial growth factor; XIAP, X-linked inhibitor of apoptosis protein
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