Hypomethylating agents in MDS
Table modified from Steensma and Stone, 2009.50
N, Number of patients treated with drug.
*Response by IWG 2000 criteria.
NA, data not available.
AZA 7-day; 75mg/m2 SC for 7 days, every 4 weeks; Decitabine 3-day; 15mg/m2 IV over 3–4 hours every 8 hours, every 6 weeks; Decitabine 5-day; 20mg/m2 IV over 1 hour for 5 days (and variants with total dose of 100mg/m2/cycle in ID03–180).
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