Transport and storage of monoamine mediators in neurons and platelets. SERT mediates reuptake of serotonin (5-HT) in neurons as well as uptake into platelets and is inhibited by tricyclic antidepressants and SSRIs.^18,79  The storage in dense vesicles is supposed to be mediated by the VMAT (SLC18A).^85,–87  The energy for this transport is provided by the function of the vacuolar H⁺-ATPase. 5-HT-R indicates serotonin receptor.