EBV is detected in monocytes and in non-B, non-T, and non-monocyte cells. (A) PBMCs stained by Immuno-FISH from patient 5 shows EBV in monocytes. EBV DNA was identified with the biotinylated FISH probe and streptavidin-conjugated Alexa 488, T cells using Alexa 594–conjugated anti-CD3, B cells using a combination of Alexa 647–conjugated anti-CD19 and anti-CD20 antibodies, and monocytes with V450-conjugated anti-CD14 antibody. Arrow indicates EBV-positive cell. (B) PBMCs stained by Immuno-FISH from patient 6 shows EBV in non-B, non-T, and non-monocyte cells. Arrow indicates EBV-positive cell.