c-MYC–dependent IL-4–inducible genes. Expression levels relative to resting macrophages (M0) in macrophages exposed to 20 ng/mL of IL-4, in the presence of the c-MYC inhibitor 10058-F4 (□; 60μM) or its vehicle (■), of SCARB1, ALOX15, MRC1, CTSC, CD209, PPARγ, AKAP12, MAOA, WNT5A, STAT6, CCL18, and PCSK5 (panels A through L, respectively). Expression levels relative to resting macrophages (M0) in macrophages exposed to 20 ng/mL of IFN-γ plus 10 ng/mL of LPS in the presence (□) or absence (■) of the c-MYC inhibitor 10058-F4 (60μM) of CCR7 and CD80 (panels M and N, respectively). Results are shown as means ± SD of n = 5 independent experiments.