Figure 2
Figure 2. Functional retroviral expression of the AURKA207-215–specific TCR. (A) Schematic representation of the luciferase assay using AURKA207-215–specific TCR-transduced Jurkat/MA cells. NFAT indicates nuclear factor activated T cells; and NK, natural killer. (B) AURKA207-215–specific TCR-transduced Jurkat/MA cells express Vβ12 but label poorly with cognate tetramer (data not shown), probably because of the low levels of surface CD8α expression. (C) AURKA207-215–specific TCR-transduced Jurkat/MA cells were stimulated with peptide-pulsed C1R-A2 cells as shown and subjected to luciferase assay. Error bars represent SDs.

Functional retroviral expression of the AURKA207-215–specific TCR. (A) Schematic representation of the luciferase assay using AURKA207-215–specific TCR-transduced Jurkat/MA cells. NFAT indicates nuclear factor activated T cells; and NK, natural killer. (B) AURKA207-215–specific TCR-transduced Jurkat/MA cells express Vβ12 but label poorly with cognate tetramer (data not shown), probably because of the low levels of surface CD8α expression. (C) AURKA207-215–specific TCR-transduced Jurkat/MA cells were stimulated with peptide-pulsed C1R-A2 cells as shown and subjected to luciferase assay. Error bars represent SDs.

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