Figure 2
Figure 2. Diagrams with frequencies of cooperating mutations in RUNX1wt compared with RUNX1-mutated cases in the NK group and the +13 group. The inner circles demonstrate all cases with a certain karyotype that are analyzed for RUNX1 mutations in the NK group (A) and the +13 group (B). In dark gray the percentages of RUNX1wt and in red the percentages of RUNX1 mutated are indicated in the inner circle. The segments in the periphery indicate the percentages of cases with other mutations for RUNX1wt and RUNX1mut subcohorts, respectively. Because some cases have > 1 additional mutation there are overlapping segments in the periphery. In some cases not all markers were analyzed, as indicated by *. Further details are given in supplemental Table 1 and supplemental Figure 1.

Diagrams with frequencies of cooperating mutations in RUNX1wt compared with RUNX1-mutated cases in the NK group and the +13 group. The inner circles demonstrate all cases with a certain karyotype that are analyzed for RUNX1 mutations in the NK group (A) and the +13 group (B). In dark gray the percentages of RUNX1wt and in red the percentages of RUNX1 mutated are indicated in the inner circle. The segments in the periphery indicate the percentages of cases with other mutations for RUNX1wt and RUNX1mut subcohorts, respectively. Because some cases have > 1 additional mutation there are overlapping segments in the periphery. In some cases not all markers were analyzed, as indicated by *. Further details are given in supplemental Table 1 and supplemental Figure 1.

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