Figure 2
Figure 2. Correlation and association studies among markers of oxidative stress and different markers related to autoimmunity, inflammation, and thrombosis in APS (statistical test: Pearson correlation analysis). (A) Positive correlation between levels of anticardiolipin antibodies of IgG isotype and the percentage of cells with impaired Δψm (depolarized mitochondria). (B) Positive correlation between peroxide levels in monocytes and cell surface expression of TF. (C) Positive correlation between peroxide levels in monocytes and plasma levels of tPA. (D) Negative correlation between plasma VEGF-A levels and TAC. (E) Relationship between the occurrence of thrombotic events and the levels of aCL antibodies of IgG isotype. Asterisk (*) indicates significant differences versus patients without thrombosis (P < .05). (F) Relationship between the occurrence of thrombotic events and the percentage of cells with depolarized mitochondria. (G) Relationship between the occurrence of thrombotic events and the levels of TAC in plasma.

Correlation and association studies among markers of oxidative stress and different markers related to autoimmunity, inflammation, and thrombosis in APS (statistical test: Pearson correlation analysis). (A) Positive correlation between levels of anticardiolipin antibodies of IgG isotype and the percentage of cells with impaired Δψm (depolarized mitochondria). (B) Positive correlation between peroxide levels in monocytes and cell surface expression of TF. (C) Positive correlation between peroxide levels in monocytes and plasma levels of tPA. (D) Negative correlation between plasma VEGF-A levels and TAC. (E) Relationship between the occurrence of thrombotic events and the levels of aCL antibodies of IgG isotype. Asterisk (*) indicates significant differences versus patients without thrombosis (P < .05). (F) Relationship between the occurrence of thrombotic events and the percentage of cells with depolarized mitochondria. (G) Relationship between the occurrence of thrombotic events and the levels of TAC in plasma.

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