AMD3100-promoted reversion of lymphoneutropenia in Cxcr4^+/1013 mice. (A) Absolute numbers of total leukocytes, CD19⁺ B cells, and Gr1⁺ neutrophils were determined in the blood 3 hours after intraperitoneal injection of AMD3100 (+) or PBS (−). (B) Absolute numbers of total BM cells, CD19⁺ B cells, and SSC^highGr1⁺ neutrophils were simultaneously determined from 1 tibia. Results of all analyzed littermates are shown (A-B). Lines indicate the mean and each circle indicates an individual mouse (**P < .005; ***P < .0005 compared with PBS-treated mice).