Comparison of miRNA expression profile in CD4⁺ T cells exposed to natural or rgp120 in vitro in absence or presence of anti-gp120 mAbs. (A) Heat map shows the miRNAs whose expression was up-regulated (red) and down-regulated (green) by at least 1 log₁₀ in treated CD4⁺ T cells in comparison with untreated cells. (B) Venn diagram of miRNAs (black) that reverted to the control level, healthy CD4⁺ T lymphocytes after gp120 neutralization by anti-gp120 mAbs and that are down-regulated (green) or up-regulated (red) in treated versus untreated cells.