Improved engraftment of bystander hematopoietic cells by ectopically expressing catalase. (A) A schematic illustration of retrovirus generation, transduction into hematopoietic cells, and transplantation. (B) Improved engraftment by ectopically expressing catalase in cBMT assay. Catalase (Cat) overexpressed HSCs showed higher engraftment potential than that of control vector transduced cells. Data are mean ± SEM of relative ratios of catalase to control in the peripheral blood of 3 independent transplantation experiments. *P < .05. n = 19 in the vector group; n = 13 in the Cat group (3 experiments in total).